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Same-Day Analysis

Ongoing Merger Effects Boost Q2 Sales, Profit at Bayer Schering Pharma

Published: 07 August 2007
German market-leader Bayer Schering Pharma's strong second-quarter sales should provide plenty of funding to boost the company's late-stage R&D pipeline.

Global Insight Perspective

 

Significance

Bayer HealthCare and sub-division Bayer Schering Pharma continued to perform solidly in the second quarter of 2007, with respective 64.7% and 30.2% year-on-year (y/y) rises in sales and double-digit increases in operating income.

Implications

The impressive sales growth figures continue to be inflated following the acquisition of Schering AG just under one year ago. However, a cooling-off of Bayer Schering's top drugs lies ahead, as top-seller Betaferon's turnover growth is rapidly diminishing in the face of nearing patent expiry.

Outlook

New drugs are the answer for Bayer Schering Pharma, and oncology hopeful Nexavar is already showing signs of becoming one of the company's most important products. With a pipeline rich in late-stage compounds, the future still looks bright for Germany's pharma champion.

Leading German pharmaceutical player Bayer continues to impress, with second-quarter (Q2) figures released today indicating a 64.7% year-on-year (y/y) leap in net sales at Bayer HealthCare amounting to 3.7 billion euro (US$5.1 billion). This growth spurt was matched for the first half of the year, which saw Bayer HealthCare gain revenues of 7.3 billion euro. Key to Bayer HealthCare's fortunes was pharmaceuticals unit Bayer Schering Pharma, formed out of Bayer's takeover of Schering AG last year. Still riding high on the post-merger wave, Bayer Schering Pharma saw stellar sales growth of 117.4% y/y to 2.6 billion euro during the second quarter and to just over 5 billion euro for the first six months of the year. In spite of special items related to ongoing acquisition costs, both Bayer HealthCare and Bayer Schering Pharma managed to post double-digit gains in operating profit, with respective increases of 21.4% y/y and 30.2% y/y during the second quarter. Conversely, parent company Bayer AG saw a rise of just 4.6% y/y in second-quarter operating profit, reaching 917 million euro, although group sales increased by 22% y/y to 8.2 billion euro in the second quarter and by 22.4% y/y to 16.6 billion euro over the first half of 2007.

Sales within the Bayer Schering Pharma unit were split between a variety of therapeutic specialities, with the Primary Care franchise holding the bulk of sales at 766 million euro during the second quarter, up by just 1.7% y/y. Next in line in terms of sales was Women's Healthcare, boosted by Schering's successful contraceptives franchise (see below), which brought in 652 million euro in second-quarter revenue. Further down the line, Bayer Schering's Haematology/Cardiology products brought in 271 million euro during the quarter, while the Oncology franchise sold 188 million euro.

Outside of Bayer Schering Pharma, Bayer HealthCare's Consumer Health division increased by 6.1% y/y (or 9.6% y/y on a currency- and portfolio-adjusted basis) to 1.1 billion euro. Turnover was boosted by a strong performance in the Diabetes Care Division, which profited from the solid market take-up of new blood-glucose monitoring systems Ascensia Contour and Ascensia Breeze, new-generation replacements for the Ascensia Elite.

Bayer AG: Q2 and H1 2007 Financial Results (mil. euro)

 

Q2 2007

% Change, Y/Y

H1 2007

% Change, Y/Y

Net Sales

8,217

22.0

16,552

22.4

   Bayer HealthCare

3,717

64.7

7,327

64.3

      of which Bayer Schering Pharma

2,583

117.4

5,078

117.4

      Bayer Schering Pharma EBIT*

207

30.2

488

35.2

   Bayer HealthCare EBIT*

431

21.4

916

24.8

Cost of Goods Sold

-4,072

14.0

8,206

17.1

Selling Expenses

-1,919

33.1

-3,726

32.7

Research and Development (R&D) Costs

650

48.1

1,275

49.5

General Administration Costs

-425

12.7

-861

17.9

Other Operating Income

228

36.5

371

-1.1

Other Operating Expenses

-462

134.5

763

32.2

Operating Result (EBIT)

917

4.6

2,092

8.6

After special items.
Source: Bayer AG.

Schering products continue to dominate Bayer Schering Pharma's list of top-selling drugs, with multiple sclerosis treatment Betaferon/Betaseron accounting for 256 million euro in turnover during the second quarter and the Yasmin contraceptives franchise bringing in 250 million euro. However, while combined sales of Yasmin, YAZ and Yasminelle have risen by some 38.1% y/y when compared with Schering AG's second-quarter 2006 results, the Betaferon franchise has recorded comparative growth of just 2.8% y/y; a worrying sign for Bayer Schering Pharma's best-selling product as it approaches patent expiry by the end of the decade. While other products fared better, losses were also felt for respiratory antibiotic Avalox/Avelox (moxifloxacin HCI; down 5.3% y/y) and antibiotic cipro/Ciprobay (ciprofloxacin; down 26.8% y/y). Sales of diagnostics products formerly owned by Schering AG have also recorded contracting sales during the quarter.

One area of hope for Bayer Schering, however, lies in kidney-cancer treatment Nexavar (sorafenib), which has at last made it onto the company's list of best-selling products after just over a year on the market. Coming in at number 13, Nexavar's second-quarter sales grew by 160.9% y/y to reach 60 million euro, and saw a rise of 148.8% y/y to 107 million euro in turnover during the first six months of 2007. Bayer Schering submitted regulatory applications for the marketing approval of Nexavar in a new indication, liver cancer, at the end of June in both the United States and the European Union.

Q2 and H1 Net Sales of Bayer Schering Pharma Top 15 Products (mil. euro)

Brand

Q2 2007

% Change, Y/Y

% Change, Y/Y (Currency Adjusted)

H1 2007

% Change, Y/Y

% Change, Y/Y (Currency Adjusted)

Betaferon/Betaseron

256

N/A

N/A

500

N/A

N/A

Yasmin/YAZ/Yasminelle

250

N/A

N/A

490

N/A

N/A

Kogenate

210

17.3

20.1

411

7.3

11.1

Adalat

162

-5.3

0.5

307

-6.4

-0.1

Avalox/Avelox

90

2.3

4.0

218

0.0

3.9

Cipro/Ciprobay

93

-26.8

-24.3

201

-22.4

-19.6

Mirena

88

N/A

N/A

169

N/A

N/A

Levitra

81

11.0

15.0

165

9.3

14.8

Magnevist

74

N/A

N/A

154

N/A

N/A

Glucobay

79

3.9

7.8

151

-1.3

3.2

Ultravist

64

N/A

N/A

119

N/A

N/A

CardioAspirin

57

7.5

12.4

111

9.9

14.1

Nexavar

60

160.9

167.6

107

148.8

157.5

Iopamiron

57

N/A

N/A

104

N/A

N/A

Diane

43

N/A

N/A

88

N/A

N/A

Total

1,664

N/A

N/A

3,295

N/A

N/A

Top-Selling Schering Products, Pro Forma (mil. euro)

Betaferon/Betaseron

256

2.8

5.6

500

4.0

7.7

Yasmin/YAZ/Yasminelle

250

38.1

43.1

490

35.7

42.1

Mirena

88

17.3

21.3

169

18.2

23.1

Magnevist

74

-12.9

-9.4

154

-4.3

0.6

Ultravist

64

-9.9

-9.9

119

-16.8

-15.4

Iopamiron

57

-8.1

0.0

104

-5.5

3.6

Diane

43

-4.4

-2.2

88

-4.3

-2.2

Source: Bayer AG.

Outlook and Implications

Prior to the release of its second-quarter results, Bayer had already seen fit to raise the bar on its forecast for Bayer HealthCare's full-year EBITDA (earnings before interest, taxation, depreciation and amortisation) margin before special items to 25%, up from 24%. By 2009, the EBITDA margin before special items is due to reach 29%. Beyond this, Bayer has remained vague on financial guidance, saying only that it hopes to achieve synergies stemming from the Bayer-Schering merger of more than 900 million euro by 2009, up from the previous forecast of 800 million euro in synergies. Besides Nexavar, Bayer Schering also has a well-stocked stable of late-stage pipeline compounds, with products such as Xarelto (rivaroxaban) showing particular promise (see Germany: 9 July 2007: Bayer Schering's Phase III Trials Report Superior Efficacy of Rivaroxaban over Enoxaparin in VTE Patients). There are currently three Phase III clinical trials in progress on rivaroxaban, and a U.S. regulatory filing for the drug as a potential preventive treatment for venous thromboembolism is expected by the end of this year. Two separate Phase III studies are also being carried out on Nexavar, both in non-small-cell lung cancer and advanced melanoma, although previous study data have hinted at disappointment in this setting (see Germany: 5 December 2006: First Chink in Nexavar's Armour as Bayer's Phase III Endpoints Not Met).
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